Steroids and derivatives
Medchemexpress LLC Trans-doxercalciferol | 74007-20-8 | MFCD01076571 | 98.2% | 412.65 | C28H44O2 | 10 MG
trans-Doxercalciferol is an isomer of doxercalciferol (a vitamin D2 analog) that activates the vitamin D receptor (VDR). Supplied as a research-grade powder for in vitro and analytical use, it has a molecular weight of 412.65 g/mol and a reported purity of 98.2%.
- Is an isomer of doxercalciferol and a vitamin D2 analog.
- Activates the vitamin D receptor (VDR) and is used in vitamin D signaling research.
- High reported purity (98.2%).
- Available in multiple pack sizes, including 10 mg.
- Powder storage: -20°C for long-term, 4°C for short-term stability.
Medchemexpress LLC Thymidine-α,α,α-d3 | 74848-84-3 | 245.25 | 1 MG
Thymidine-d3 is deuterium labeled Thymidine, a specific precursor of deoxyribonucleic acid used as a cell synchronizing agent. It functions as a DNA synthesis inhibitor, capable of arresting cells at the G1/S boundary before DNA replication. Deuterium substitution has the potential to affect pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Apexbio Technology LLC Vitamin D3(Synonyms: Cholecalciferol, Calciol, Vitamin D₃, Colecalciferol, Activated 7-Dehydrocholesterol), 5g, CAS: 67-97-0.
Vitamin D3 (Cholecalciferol CAS 67-97-0) is an endogenous fat-soluble vitamin that serves as a precursor requiring metabolic conversion to its biologically active metabolite Following hydroxylation the active form exerts its function predominantly by binding the nuclear vitamin D receptor (VDR) modulating gene expression pathways involved in cellular differentiation and proliferation Research indicates that activated Cholecalciferol promotes cellular differentiation and exhibits anti-proliferative effects against various cancer cell types Consequently Vitamin D3 is frequently utilized in biomedical research studying mechanisms underlying tumor development and differentiation pathways
Medchemexpress LLC Cyclin D3/CCND3 Antibody (YA484) | Predicted band size: 33 kDa; Observed band size: 33 kDa | 50 UL
Cyclin D3/CCND3 Antibody (YA484) | Predicted band size: 33 kDa; Observed band size: 33 kDa | 50 UL
Cambridge Isotope Laboratories VITAMIN D3 (CHOLECALCIFEROL) UNLABELED 100 UG/ML IN ETHANOL, 1 ML
VITAMIN D3 (CHOLECALCIFEROL) UNLABELED 100 UG/ML IN ETHANOL, 1 ML
Medchemexpress LLC Betaine-d3 chloride | 1219349-47-9 | 156.63 | 5 MG
Betaine-d3 chloride is the deuterium labeled Betaine chloride. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences 2 Keto 3 methyl d3 butyrc500MG
2 Keto 3 methyl d3 butyrc500MG
Medchemexpress LLC HY-15267B 1mg Medchemexpress, (24S)-MC 976 CAS:112849-14-6 Purity:>98%
Medchemexpress, HY-15267B 1mg (24S)-MC 976 CAS:112849-14-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cambridge Isotope Laboratories 2 6-Dinitrotoluene (methyl-D3 98%) 1 mg/mL in acetonitrile 1 mL
2 6-Dinitrotoluene (methyl-D3 98%) 1 mg/mL in acetonitrile 1 mL
Cambridge Isotope Laboratories 1 25-Dihydroxyvitamin D2 (unlabeled) CP 95% 1 mg
1 25-Dihydroxyvitamin D2 (unlabeled) CP 95% 1 mg
MOLECULAR DEPOT LLC 25-OH Vitamin D3 Biotin - 1 mg
25-OH Vitamin D3 Biotin Conjugate consists of 25-OH Vitamin D3 conjugated to Biotin via a 22 A spacer arm The spacer adds flexibility to the 25-OH Vitamin D3 moiety which is required for its interaction with specific antibodies and other binding partners This compound has been tested for use in several 25-OH Vitamin D applications including ELISA The conjugate is supplied as a DMSO stock solution For in vitro research use only
Medchemexpress LLC Fluorometholone acetate | 3801-06-7 | 98.5% | 100 MG
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is a potent inhibitor of carbonic anhydrase (CA) with IC50 values of 2.18 μM for hCA-I and 17.5 μM for hCA-II. It also has an anti-inflammatory effect and has potential for research into external ocular inflammation.
- Synthetic glucocorticoid corticosteroid
- Corticosteroid ester
- Potent inhibitor of carbonic anhydrase (CA)
- Anti-inflammatory effect
- Potential for external ocular inflammation research
- For research use only
Medchemexpress LLC Z-guggulsterone | 39025-23-5 | MFCD01310757 | 99.4% | 312.45 g/mol | C21H28O2 | 5 MG
(Z)-Guggulsterone is a plant-derived sterol (CAS 39025-23-5) isolated from Commiphora mukul. It acts as a farnesoid X receptor (FXR) antagonist with reported activities including induction of apoptosis, inhibition of angiogenesis, and modulation of ACE2 expression, and is used in biochemical and cell-signaling research.
- Potent farnesoid X receptor (FXR) antagonist.
- Induces apoptosis in multiple cancer cell lines.
- Inhibits angiogenesis via the VEGF-VEGFR2-Akt pathway.
- Reported to reduce ACE2 expression and SARS-CoV-2 infection in studies.
- Suitable for biochemical and signaling pathway research applications.
Medchemexpress LLC (Z)-Guggulsterone | 39025-23-5 | 99.4% | 312.45 | 10 MG
(Z)-Guggulsterone is a constituent found in the Indian Ayurvedic medicinal plant Commiphora mukul. It functions by inhibiting the growth of human prostate cancer cells through apoptosis and hinders angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway. It also acts as a potent FXR antagonist, reducing ACE2 expression and inhibiting SARS-CoV-2 infection. This product is intended for research use only and is not sold to patients.
- Inhibits growth of human prostate cancer cells through apoptosis
- Hinders angiogenesis by suppressing VEGF-VEGF-R2-Akt signaling
- Acts as a potent FXR antagonist
- Reduces ACE2 expression
- Inhibits SARS-CoV-2 infection